发明名称 METHOD FOR PREDICTION OF HAEMATOGENIC METASTASIS IN DOUBLE-SIDED SYNCHRONOUS INVASIVE NON-SPECIFIC BREAST CARCINOMA
摘要 FIELD: medicine.SUBSTANCE: invention is intended for predicting hematogenic metastasis in case of double-sided synchronous invasive carcinoma of non-specific mammary glands. Histological assessment of infiltrative component of neoplasms tissue in both mammary glands is carried out, during which the number of different structures from 1 to 5 is calculated, among which additionally alveolar, trabecular, solid structure and discrete groups of tumour cells are defined, presence of structures in points is estimated and Y regression equation value is calculated by formula: Y=(-41.1+2.2X-1.3X-0.74X), then the value of haematogenous metastases development probability P is determined by formula: P=e/(1+e) and upon P≥50 % determine high, and upon P<50 % - low risk of haematogenous metastases development.EFFECT: method increases accuracy and information value of hematogenic metastasis prediction.1 cl, 2 ex, 2 tbl
申请公布号 RU2589287(C1) 申请公布日期 2016.07.10
申请号 RU20150103573 申请日期 2015.02.03
申请人 FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE NAUCHNOE UCHREZHDENIE "TOMSKIJ NAUCHNO-ISSLEDOVATELSKIJ INSTITUT ONKOLOGII" (TOMSKIJ NII ONKOLOGII) 发明人 ZAVYALOVA MARINA VIKTOROVNA;FESIK EVGENIYA ANATOLEVNA;KRAKHMAL NADEZHDA VASILEVNA;VTORUSHIN SERGEJ VLADIMIROVICH;SLONIMSKAYA ELENA MIKHAJLOVNA;KHRISTENKO KSENIYA YUREVNA;TELEGINA NADEZHDA SEMENOVNA
分类号 G01N33/48 主分类号 G01N33/48
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