14Alpha-hydroxy-4-androstene-3,6,17-trione hydrate crystal and process for producing same.

摘要

Provided are stable hydrate crystals of 14 alpha -hydroxy-4-androstene-3,6,17-trione having a biological activity of human placenta-originating estrodiene synthesis enzyme inhibitory action. These hydrate crystals include two kinds of 14 alpha -hydroxy-4-androstene-3,6,17-trione hydrate crystals having a diffraction pattern having characteristic peaks at diffraction angles in crystalline powder X-ray diffraction. Processes for producing these hydrate crystals are also provided. <IMAGE>