发明名称 |
OTITIS MEDIA VACCINE |
摘要 |
It has been discovered that a vaccine comprised of fimbrin, a filamentous protein derived from the bacterial surface appendages of non-typable Haemophilus influenzae is useful in studying, preventing or reducing the severity of, otitis media. The gene sequence of the DNA coding for fimbrin and the amino acid sequence of fimbrin have also been determined. Vectors containing DNA coding for fimbrin have also been developed, and transformants have been prepared which contain such vectors and which express such DNA and provide a source of pure fimbrin. |
申请公布号 |
WO9426304(A1) |
申请公布日期 |
1994.11.24 |
申请号 |
WO1994US05477 |
申请日期 |
1994.05.12 |
申请人 |
OHIO STATE RESEARCH FOUNDATION |
发明人 |
KOLATTUKUDY, PAPPACHAN, E.;BAKALETZ, LAUREN, O.;SIRAKOVA, TATIANA |
分类号 |
C12N1/21;A61K39/00;A61K39/102;A61P31/04;C07K14/08;C07K14/285;C12N5/10;C12N7/00;C12N15/09;C12N15/31;C12P21/02;C12R1/01;C12R1/19;(IPC1-7):A61K39/02;C12N15/00;C07K15/12;C07K17/00;C12N1/00;C12N1/20 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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