| 摘要 |
An osteogenesis promoter and/or osteoporosis remedy comprising, as an active ingredient, an androgen derivative represented by the following formula (1): <IMG> (I) wherein each broken line indicates that the relevant carbon-to-carbon bond is a single bond or a double bond or a salt thereof. The compound (1) activates osteoblasts, promotes osteogenesis and increases the bone mass, so that it is used for the treatment of a morbid condition of lowered osteogenesis due to aging, immobilization, administration of glucocorticoids and so forth. Further, it can increase the bone mass by its osteogenesis promoting effect so that it is useful for the treatment of osteoporosis accompanying the above morbid condition or occurring after ovariectomy or menopause.
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