发明名称 STABILISATION OF PHARMACOLOGICALLY ACTIVE COMPOUNDS IN SUSTAINED RELEASE COMPOSITIONS
摘要 A pharmaceutical composition comprises as the active agent a peptide in association with embonic acid or ascorbic acid or a salt thereof, excluding 1) ACTH in association with embonic acid or ascorbic acid or a salt thereof and 2) a LHRH active compound in association with ascorbic acid or a salt thereof, in a matrix of a polylactide, having a lactide/glycolide molar ratio of from 100:0 to 40:60, a Mw of from 10.000 to 200.000 and a polydispersity of from 1.7 to 3.0. It is used for sustained release.
申请公布号 CA2123144(A1) 申请公布日期 1994.11.11
申请号 CA19942123144 申请日期 1994.05.09
申请人 BODMER, DAVID;GENGENBACHER, THOMAS;ESPARZA, INMACULADA 发明人 BODMER, DAVID;GENGENBACHER, THOMAS;ESPARZA, INMACULADA
分类号 A61K9/52;A61K9/14;A61K9/16;A61K35/74;A61K38/00;A61K38/09;A61K38/16;A61K39/00;A61K39/08;A61K47/12;A61K47/22;A61K47/26;A61K47/34;C07K14/005;C07K14/195;C07K14/33;C07K14/575;C07K14/59;C07K14/72;(IPC1-7):C07K14/695;A61K38/35;C07K7/23 主分类号 A61K9/52
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