摘要 |
The invention relates to novel amino acid derivatives of the formula I <IMAGE> and their pharmaceutically acceptable salts, wherein the group R<2> is <IMAGE> and R<1>, A, R<3>, R<4>, R<5>, R<6>, X, Y, Z, m and n have the meanings indicated in the description, and their preparation and use. The novel compounds are useful neurokinin (tachykinin) antagonists.
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申请人 |
BOEHRINGER INGELHEIM KG, 55218 INGELHEIM, DE |
发明人 |
SCHNORRENBERG, GERD, DIPL.-CHEM. DR., 55435 GAU-ALGESHEIM, DE;ESSER, FRANZ, DIPL.-CHEM. DR., 55218 INGELHEIM, DE;DOLLINGER, HORST, DIPL.-CHEM. DR., 55128 INGELHEIM, DE;JUNG, BIRGIT, DR., 55411 BINGEN, DE;BUERGER, ERICH, DIPL.-BIOL. DR., 55411 BINGEN, DE |