发明名称 Novel amino acid derivatives, process for their preparation and pharmaceutical compositions containing these compounds
摘要 The invention relates to novel amino acid derivatives of the formula I <IMAGE> and their pharmaceutically acceptable salts, wherein the group R<2> is <IMAGE> and R<1>, A, R<3>, R<4>, R<5>, R<6>, X, Y, Z, m and n have the meanings indicated in the description, and their preparation and use. The novel compounds are useful neurokinin (tachykinin) antagonists.
申请公布号 DE4315437(A1) 申请公布日期 1994.11.10
申请号 DE19934315437 申请日期 1993.05.08
申请人 BOEHRINGER INGELHEIM KG, 55218 INGELHEIM, DE 发明人 SCHNORRENBERG, GERD, DIPL.-CHEM. DR., 55435 GAU-ALGESHEIM, DE;ESSER, FRANZ, DIPL.-CHEM. DR., 55218 INGELHEIM, DE;DOLLINGER, HORST, DIPL.-CHEM. DR., 55128 INGELHEIM, DE;JUNG, BIRGIT, DR., 55411 BINGEN, DE;BUERGER, ERICH, DIPL.-BIOL. DR., 55411 BINGEN, DE
分类号 A61K38/00;C07K5/02;C07K5/078;(IPC1-7):C07D401/14;C07C237/00;C07D403/14;C07D409/14;C07D491/056;C07D491/113;C07D215/38;C07D209/40;C07D223/16;C07D401/12;C07D403/12;A61K31/505 主分类号 A61K38/00
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