16 alpha ,17 alpha -ACETAL GLUCOCORTICOSTEROIDAL DERIVATIVES

摘要

New 16 alpha ,17 alpha -acetal glucocorticosteroid derivatives of general formula (I), wherein dotted line in the 1,2-position represents optional bond, R represents hydrogen atom or acetyl group and R1 and R2 represent independently hydrogen atom or fluorine atom, and their solvates with organic solvents, with antiinflammatory, antiallergic and immunosuppressive activities, the process for their preparation and pharmaceutical compositions containing them.