| 发明名称 |
Altered affinity polypeptides of metal chelate binding antibodies. |
| 摘要 |
<p>This invention provides a polypeptide having an amino acid sequence including a complementarity determining region (CDR) sequence of a native antibody having an amino acid substitution, the polypeptide having a binding affinity for a metal chelate of EDTA or an EDTA analog that is about equal to or altered from the binding affinity of the native antibody.</p> |
| 申请公布号 |
EP0623675(A1) |
申请公布日期 |
1994.11.09 |
| 申请号 |
EP19930308960 |
申请日期 |
1993.11.10 |
| 申请人 |
HYBRITECH INCORPORATED |
发明人 |
AHRWEILER, PATRICIA MARIE;MOORE, MARGARET DOW |
| 分类号 |
A61K47/48;A61K39/395;A61P35/00;C07K16/00;C07K16/30;C07K16/44;C12N1/21;C12N5/10;C12N15/09;C12R1/19;C12N15/13;C12P21/08;C12R1/91;G01N33/53;G01N33/531;(IPC1-7):C12N15/13;A61K49/02 |
主分类号 |
A61K47/48 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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