发明名称 |
ORNITHINE DECARBOXYLASE INHIBITING CYCLIC AMINOOXY COMPOUNDS |
摘要 |
2135782 9424093 PCTABS00034 Compounds of the formula (I): H2N-(CH2)n-A-(CH2)m-O-NH2 and salts thereof are described in which the radical A is C3-C6cycloalkylene; n is 0 or 1 and, independently thereof, m is 0 or 1; with the provisos that a) the distance between the aminooxy radical H2N-O- and the amino group -NH2 is at least 3 and not more than 4 carbon atoms and that b) the two radicals H2N-(CH2)n- and -(CH2)m-O-NH2 are not bonded to the same ring carbon atom of A. The compounds of formula (I) and their salts are ornithine decarboxylase inhibitors.
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申请公布号 |
CA2135782(A1) |
申请公布日期 |
1994.10.27 |
申请号 |
CA19942135782 |
申请日期 |
1994.04.02 |
申请人 |
CIBA-GEIGY AG |
发明人 |
FREI, JOERG;STANEK, JAROSLAV |
分类号 |
A61K31/13;A61P33/02;A61P35/00;A61P43/00;C07C239/08;C07C239/20;(IPC1-7):C07C239/20 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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