发明名称 Heterocyclic compounds as platelet aggregation inhibitors
摘要 A compound of the general formula(M1)n-Q-(M2)1-n-L-AIwherein: n is 0 or 1; M1 is an amino group; Q is an aromatic heterocyclic group containing a basic nitrogen atom; M2 is an imino group; L is a template group; and A is an acidic group, or an ester or amide derivative thereof, or a sulphonamide group; and pharmaceutically acceptable salts and pro-drugs thereof, for use in the treatment of a disease in which platelet aggregation mediated by the binding of adhesion molecules to GPIIb-IIIa is involved. Novel compounds are also disclosed.
申请公布号 AU6289094(A) 申请公布日期 1994.10.24
申请号 AU19940062890 申请日期 1994.03.28
申请人 ZENECA LIMITED 发明人 MICHAEL GARTH WAYNE;MICHAEL JAMES SMITHERS;JOHN WALL RAYNER;ALAN WELLINGTON FAULL;ROBERT JAMES PEARCE;ANDREW GEORGE BREWSTER;RICHARD EDEN SHUTE;STUART DENNETT MILLS;PETER WILLIAM RODNEY CAULKETT
分类号 A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4418;A61K31/4427;A61K31/445;A61K31/4545;A61K31/47;A61K31/505;A61K31/5377;A61P7/02;A61P43/00;C07D213/74;C07D213/81;C07D215/14;C07D215/42;C07D239/42;C07D401/04;C07D401/12;C07D401/14;C07D405/12;C07D521/00 主分类号 A61K31/44
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