发明名称 HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS
摘要 Compounds of formula (I) and metabolically labile esters and amides thereof, and pharmaceutically acceptable salts thereof, in which R<13>, M<2>, X<1>, Z<1>, Z<1a>, X<2> and A<1> have the meanings given in the specification. The compounds are useful as inhibitors of the binding of fibrinogen to glycoprotein IIb/IIIa. Novel intermediates are also disclosed.
申请公布号 WO9422834(A1) 申请公布日期 1994.10.13
申请号 WO1994GB00647 申请日期 1994.03.28
申请人 ZENECA LIMITED 发明人 WAYNE, MICHAEL, GARTH;SMITHERS, MICHAEL, JAMES;RAYNER, JOHN, WALL;FAULL, ALAN, WELLINGTON;PEARCE, ROBERT, JAMES;BREWSTER, ANDREW, GEORGE;SHUTE, RICHARD, EDEN;MILLS, STUART, DENNETT;CAULKETT, PETER, WILLIAM, RODNEY
分类号 A61K31/44;A61K31/4409;A61K31/4418;A61P7/02;C07D213/74 主分类号 A61K31/44
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