发明名称 |
Squaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
摘要 |
The present invention provides substituted dibenzoxazepine compounds of Formula I: <IMAGE> Formula I which are useful as analgesic agents for the treatment of pain, and as prostaglandin-E2 antagonists for the treatment of prostaglandin-E2 mediated diseases, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, a method for eliminating or ameliorating pain in an animal, and a method for treating prostaglandin-E2 mediated diseases in an animal, comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
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申请公布号 |
US5354746(A) |
申请公布日期 |
1994.10.11 |
申请号 |
US19930069503 |
申请日期 |
1993.06.01 |
申请人 |
G. D. SEARLE & CO. |
发明人 |
CHANDRAKUMAR, NIZAL S.;PITZELE, BARNETT S. |
分类号 |
C07D267/20;C07D413/12;(IPC1-7):C07D267/20;C07D281/16;C07D413/08;A61K31/55 |
主分类号 |
C07D267/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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