摘要 |
<p>Nucleic acids encoding human neuronal nicotinic acetylcholine receptor alpha and beta subunits, mammalian and amphibian cells containing said nucleic acids, methods for producing alpha and beta subunits and recombinant (i.e., isolated or substantially pure) alpha subunits (specifically α4 and α7) and beta subunits (specifically β4) are provided. In addition, combinations of subunits (i.e., α1, α2, α3, α4, and/or α7 subunits in combination with β4 subunits; or β2, β3 and/or β4 subunits in combination with α4 and/or α7 subunits) are provided.</p> |