| 发明名称 |
SPIROAZACYCLIC DERIVATIVES AS SUBSTANCE P ANTAGONISTS |
| 摘要 |
The present invention relates to novel spirocyclic piperidine derivatives and related compounds and, specifically, to compounds of formula (I) wherein X, Z, Y, R<1>, R<2>, R<3>, R<4> and m are as defined in the specification, and to intermediates used in the synthesis of such compounds. The novel compounds of formula (I) are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders. |
| 申请公布号 |
WO9420500(A1) |
申请公布日期 |
1994.09.15 |
| 申请号 |
WO1993US11793 |
申请日期 |
1993.12.10 |
| 申请人 |
PFIZER INC.;DESAI, MANOJ, C.;VINCENT, LAWRENCE, A. |
发明人 |
DESAI, MANOJ, C.;VINCENT, LAWRENCE, A. |
| 分类号 |
A61K31/435;A61P25/00;A61P25/04;A61P25/30;A61P29/00;C07D211/76;C07D471/10;(IPC1-7):C07D471/10;C07D487/10;C07D491/107;C07D221/20;C07D209/96;A61K31/40 |
主分类号 |
A61K31/435 |
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