摘要 |
<p>A single phase topical anaesthetic compositions for sore throat treatment comprising: a) from about 0.1 % to about 2 % by weight of benzocaine; b) from about 25 % to about 55 % by weight of humectant selected from polyethylene glycol having a molecular weight of less than 1500, propylene glycol, glycerol and mixtures thereof; c) from about 43 % to about 74.9 % by weight of a mixture of water and lower (C1-C4) alcohol in a weight ratio of from about 0.3:1 to 3:1. The compositions display improved physical stability, benzocaine chemical stability and anaesthetic efficacy.</p> |