发明名称 |
Parasiticidal milbemycin derivatives, a process for their production, and compositions containing the same. |
摘要 |
Compounds of formula (I): <CHEM> wherein R<1> is hydrogen or methyl, R<2> is hydrogen or E 2-methyl 2-butenoyloxy, and R<3> is hydrogen or hydroxy, with the proviso that when R<3> is hydrogen, R<1> and R<2> are both hydrogen, and when R<2> is E 2-methyl 2-butenoyloxy, R<1> is methyl; the compound of formula (II): <CHEM> and the compound of formula (III): <CHEM> are obtainable by the fermentation of Streptomyces E225 NC1B 12310 or Streptomyces E225B NC1B 12509. The compounds have anthelmintic utility. |
申请公布号 |
EP0254583(B1) |
申请公布日期 |
1994.09.07 |
申请号 |
EP19870306547 |
申请日期 |
1987.07.24 |
申请人 |
BEECHAM GROUP PLC |
发明人 |
BANKS, RHONA MARY;POULTON, MARK EDWARD;BAKER, GEOFFREY HAROLD;DORGAN, RODERICK JOHN |
分类号 |
A61K31/365;A01N43/90;A01N49/00;A01N63/02;A23K20/195;A61P33/00;A61P33/10;C07D493/22;C07H17/08;C07H19/01;C12P17/18;C12R1/465 |
主分类号 |
A61K31/365 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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