发明名称 |
Method for recovering L-phenylalanine. |
摘要 |
<p>The present invention provides crystals of L-phenylalanine monomethyl sulfate which have low solubility compared to L-tyrosine and D-phenylalanine. The L-phenylalanine monomethylsulfate crystals are obtained by subjecting a solution containing monomethyl sulfuric acid and phenylalanine to crystallization. Further, the present invention also provides a process for recovering L-phenylalanine from a water layer by neutralizing the esterified reaction, extracting an ester of L-phenylalanine therefrom with an organic solvent, and recovering remaining L-phenylalanine in the water layer as L-phenylalanine monomethylsulfate. L-phenylalanine monomethyl sulfate is obtained by esterifying L-phenylalanine and methanol in the presence of sulfuric acid, neutralizing the esterified solution with a base in the presence of water, extracting the produced L-phenylalanine methyl ester from the neutralized solution with an organic solvent, and then crystallized the resultant water layer under acidic condition.</p> |
申请公布号 |
EP0612717(A1) |
申请公布日期 |
1994.08.31 |
申请号 |
EP19940101925 |
申请日期 |
1994.02.08 |
申请人 |
AJINOMOTO CO., INC. |
发明人 |
TAKEMOTO, TADASHI, C/O CENTRAL RESEARCH LAB.;HIJIYA, TOYOTO, C/O CENTRAL RESEARCH LAB.;YONEKAWA, TERUO, C/O CENTRAL RESEARCH LAB.;MOCHIZUKI, CHIAKI, C/O CENTRAL RESEARCH LAB. |
分类号 |
C07C227/40;C07C227/42;C07C229/36;(IPC1-7):C07C229/34 |
主分类号 |
C07C227/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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