发明名称 |
METHODS FOR THE DIAGNOSIS OF DIABETES AND PREDIABETIC CONDITIONS |
摘要 |
A method for detecting a autoantibodies to glutamic acid decarboxylase (GAD) in the serum of a patient as diagnostic of a diabetic or prediabetic condition in the patient, comprises contacting a serum sample from the patient with a GAD antigen and detecting binding of autoantibodies to GAD in the sample by the GAD antigen, wherein the GAD antigen comprises a GAD preparation containing an enhanced amount of dimer(s) or oligomer(s) of the 65 kD and/or 67 kD isoforms of GAD. A diagnostic kit is also disclosed.
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申请公布号 |
CA2155677(A1) |
申请公布日期 |
1994.08.18 |
申请号 |
CA19942155677 |
申请日期 |
1994.02.09 |
申请人 |
MONASH UNIVERSITY |
发明人 |
MACKAY, IAN REAY;ROWLEY, MERRILL JOY;ZIMMET, PAUL ZEV |
分类号 |
C12N9/88;G01N33/564;G01N33/573;(IPC1-7):C12N9/88 |
主分类号 |
C12N9/88 |
代理机构 |
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地址 |
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