| 发明名称 |
PIPERAZIDES OF SUBSTITUTED PHENYLALANINE DERIVATES AS THROMBIN INHIBITORS |
| 摘要 |
The present invention relates to D,L-, L- and D-phe-nylalanine piperazides of formula (I) defined in claim 1 that inhibit blood coagulation, and thrombin and/or trypsin, respectively. The compounds are extraordinarily absorbable after oral, intraduodenal and in particular rectal administration and show only a low toxicity.
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| 申请公布号 |
CA2133761(A1) |
申请公布日期 |
1994.08.18 |
| 申请号 |
CA19942133761 |
申请日期 |
1994.02.09 |
| 申请人 |
PENTAPHARM AG |
发明人 |
STUERZEBECHER, J RG;VIEWEG, HELMUT;WIKSTROEM, PETER;ADLER, CHRISTOPH |
| 分类号 |
C07D295/18;A61K31/44;A61K31/4402;A61K31/495;A61P7/02;C07D213/74;C07D239/04;C07D295/185;C07D295/20;C07D311/70;C07D333/24;(IPC1-7):C12P41/00;C07D401/00;C07D403/00;C07D405/00;C07D409/00;C07D413/00;A61K31/535 |
主分类号 |
C07D295/18 |
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