发明名称 HUMAN-MURINE CHIMERIC ANTIBODIES AGAINST RESPIRATORY SYNCYTIAL VIRUS
摘要 This invention relates to a human antibody which contains at least one CDR from each variable heavy and variable light chain of at least one murine monoclonal antibody, (preferably a neutralizing antibody) against respiratory syncytial virus. The invention also relates to the murine antibody being an antibody against RSV-F protein. In a preferred embodiment the CDR contains three complementarity determining regions from the variable heavy and variable light chain of at least one murine antibody against RSV-F protein.
申请公布号 WO9417105(A1) 申请公布日期 1994.08.04
申请号 WO1993US01168 申请日期 1993.01.29
申请人 MEDIMMUNE, INC. 发明人 JOHNSON, LESLIE
分类号 C07K16/10;C12P21/08;(IPC1-7):C07K15/28;A61K39/42;A61K39/395;C12N5/28;C12N5/20 主分类号 C07K16/10
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