COMPOSITION CONTAINING NANOPARTICLE AND ITS MANUFACTURE

摘要

PURPOSE: To produce a compsn. for medical treatment or diagnosis having a regulated cloud point. CONSTITUTION: This compsn. contains nano-particles having a purified polymer surfactant adsorbed on the surfaces as a surface modifying agent and contg. a cloud point regulating agent in a combined state. In this compsn., the cloud point regulating agent exists by an amt. enough to raise the cloud point of the surface modifying agent. The surface modifying agent is preferably a purified polyalkylene oxide substd. ethylenediamine surfactant. The cloud point regulating agent is preferably polyethylene glycol. The nano-particles are produced through a process for bringing nano-particles into contact with the cloud point regulating agent under sufficient conditions including time to raise the cloud point of the surface modifying agent.