发明名称 DITERPENES WITH IMMUNOACTIVITY CONTROLLING ACTION
摘要 The use of diterpenes of formula (I) as pharmaceutical agents is new. In (I), R1 = CH2-C(CH3) = CHR3 or CH2-CH(CH3)-CH2-R3. R3 = CH2OH, CHO, COOH or COOR4. R4 = 1-5C alkyl. A = CH-CH3 or C = CH2. R2 = H, pentose or hexose sugar, di-or oligosaccharide or an amino sugar. (I) are new as long as R1 is not -CH2-C(CH3) = CHCH2OH or -CH2-C(CH3) = CHCHO when A is C = CH2 and R2 is galactose. The use of a glycosylated derivative of (I) is specifically claimed.
申请公布号 JPH06206839(A) 申请公布日期 1994.07.26
申请号 JP19910042195 申请日期 1991.02.15
申请人 MERCK PATENT GMBH 发明人 HANSUUETSUKARUTO RAADOUNTSU;MIHIYAERU BUORUFU;MANFUREETO BAUMUGAARUTO;BUIRII KINZUI;GERUTOOARUBUREHITO RUTSUKENBATSUHA
分类号 A61K31/045;A61K31/11;A61K31/215;A61K31/70;A61K31/7028;A61K31/7034;A61K36/00;A61P37/00;C07C35/23;C07C47/19;C07C59/13;C07C59/31;C07C67/08;C07C67/40;C07C69/708;C07C69/734;C07H15/203;C07H15/207 主分类号 A61K31/045
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