| 摘要 |
<p>Piperazine derivatives of formula (I) and their pharmaceutically acceptable salts are 5-HT1A binding agents and may be used, for example, as anxiolytics. In the formula, A is an optionally substituted alkylene chain, Z is a specified bicyclic nitrogen containing heteroaromatic radical, R is hydrogen or lower alkyl, R1 is aryl or aryl(lower)alkyl and R?2 and R3¿ are hydrogen or specified organic radicals or -NR2R3 represents a heterocyclic ring.</p> |
