发明名称 RECOMBINANT ANTI-VLA4 ANTIBODY MOLECULES
摘要 The present invention discloses recombinant anti-VLA4 antibody molecules, including humanized recombinant anti-VLA4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In addition, the humanized recombinant anti-VLA4 antibodies disclosed can be useful in methods of diagnosing and localizing sites of inflammation.
申请公布号 CA2153692(A1) 申请公布日期 1994.07.21
申请号 CA19942153692 申请日期 1994.01.07
申请人 BIOGEN, INC. 发明人 LOBB, ROY R.;CARR, FRANK J.;TEMPEST, PHILIP R.
分类号 C12N15/09;A61K38/00;A61K39/395;A61P7/02;A61P9/10;A61P11/00;A61P11/06;A61P29/00;A61P31/00;A61P35/00;A61P35/02;A61P37/02;C07K14/78;C07K16/18;C07K16/28;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/00;C12N5/10;C12N15/13;C12P21/02;C12P21/08;C12R1/91;G01N33/53;G01N33/577;(IPC1-7):C12N15/13;A61K49/00;A61K51/10;C07K16/46;G01N33/564;C12N15/62 主分类号 C12N15/09
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