SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS LEUKOTRIENE ANTAGONISTS

摘要

This invention relates to compounds which are useful as leukotriene antagonists particularly LTB4 antagonists. These compounds are characterized by their having a pyridyl ring substituted at the 2 position with a lower alkyl radical which preferably has a terminal carboxyl group, a 3 position radical which can be characterized as having a fatty nature and a 6 position substituent which can be characterized as comprising a heteroaromatic group linked to the 6 position of the pyridyl ring by means of several atoms, namely, carbon or carbon and a heteroatom.