| 摘要 |
Described are caffeic acid derivatives represented by the following formula: <IMAGE> wherein either one of R1 and R2 is a hydrogen atom, a C1-C6 alkyl group, a group -CO2R4, or a group -CONR5R6, R4, R5 and R6 being either a hydrogen atom or a particular group, and the other is the group -CO2R4 or the group -CONR5R6, or R1 and R2 are coupled together to represent a 5-membered ring so formed, Y represents a particular group or atom, X represents a substituted or unsubstituted C6-C10 aryl, C7-C12 aralkyl, heterocyclic or heterocyclic ring-alkyl group, m and n stand for particular integers, and R3 represents a hydrogen atom, a hydroxyl group, a group -OCO2R7, R7 being a hydrogen atom or a particular group, or a group -OCONR8R9, R8 representing a C1-C6 alkyl group and R9 representing a hydrogen atom or a C1-C6 alkyl group, and pharmaceutically acceptable salts thereof. Therapeutic agents containing the derivatives or salts are effective for diseases of the circulatory system.
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