| 摘要 |
A process for the selective chlorination of pyridine, a lower alkyl pyridine or 3-cyanopyridine includes passing the pyridine compound, chlorine and an inert gas through a two stage reaction. In a first reaction zone, these materials are subjected to a hot spot controlled at a temperature of about 350 DEG C to about 500 DEG C. The materials are then subsequently passed through a second reaction zone at a relatively lower temperature, for example below about 340 DEG C. |
