发明名称 NOVEL ELECTROSTATIC PROCESS FOR MANUFACTURING COATED TRANSPLANTS AND PRODUCTS
摘要 <p>An electrostatic process for caoting a biological material with a uniform, continuous polymer layer by discharging a suspension of the biological material in a gellable coating solution (2) in a continuous stream (16) through an orifice. The stream is attenuated to form droplets (18) by maintaining an electrostatic voltage between the needle and the gelling solution which is sufficient to maintain an attraction of at least 1 x 101-6 newtons on the stream of liquid leaving the needle (8), and the droplets (18) are collected in an electroconductive solution (20). A preferred product is pancreatic islets having a continuous, smooth coating of high polymannuronate non-fibrogenic alginate having a thickness of at least 10 νm. A DC power supply (12) provides the required voltage.</p>
申请公布号 WO1994013266(A1) 申请公布日期 1994.06.23
申请号 US1993005090 申请日期 1993.06.01
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