Synthesis of sulfated polyhydroxy fatty acid amide surfactants

摘要

Polyhydroxy fatty acid amide nonionic surfactants are converted in high yields to their sulfated analog surfactants using an SO3/pyridine complex as a sulfating agent. Thus, C12-C18 N-methyl glucamide is sulfated in methylene chloride or pyridine solvent to form the corresponding sulfated glucamide in yields of 80% or higher.