发明名称 TREATMENTS EMPLOYING VASOCONSTRICTIVE SUBSTANCES IN COMBINATION WITH CYTOTOXIC AGENTS FOR INTRODUCTION INTO CELLULAR LESION AREAS
摘要 TREATMENTS EMPLOYING VASOCONSTRICTIVE SUBSTANCES IN COMBINATION WITH CYTOTOXIC AGENTS FOR INTRODUCTION INTO CELLULAR LESION AREAS A pharmaceutical composition and method of treating cellular disorders involving abnormal solid cellular growths which comprises administering a pharmaceutical composition containing cytotoxic agents in combination with a vasoconstrictive drug. Enhanced effectiveness of the composition is observed, with reduced cytotoxic effects on cells distant from the site of introduction. Agents may be included to enhance therapeutic gain and reduce adverse affects to normal tissue.
申请公布号 CA1330295(C) 申请公布日期 1994.06.21
申请号 CA19880578596 申请日期 1988.09.27
申请人 MATRIX PHARMACEUTICALS, INC. 发明人 LUCK, EDWARD E.;BROWN, DENNIS M.
分类号 A61K31/135;A61K31/17;A61K31/28;A61K31/48;A61K31/505;A61K31/557;A61K31/565;A61K31/57;A61K31/70;A61K33/24;A61K38/00;A61K38/28;A61K38/43;A61K38/46;A61K45/00;A61K45/06;A61P35/00;(IPC1-7):A61K31/00;A61K37/00 主分类号 A61K31/135
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