发明名称 |
Genes encoding a 3-acylation enzyme for macrolide antibiotics |
摘要 |
A DNA fragment or a restriction enzyme-digested DNA fragment, the DNA fragment containing a gene, acyA, encoding a 3-acylation enzyme for macrolide antibiotics, characterized by being derived from a strain belonging to the genus Streptomyces, having a size of about 1.8 kb or about 3.2 kb, and having a DNA base sequence shown in a restriction enzyme map shown in FIG. 1(A) or FIG. 1(B), respectively, in the attached drawing. 3-Acylated macrolide antibiotics can be produced advantageously using macrolide antibiotics-producing bacteria transformed with vector plasmids having inserted therein the DNA fragment.
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申请公布号 |
US5322937(A) |
申请公布日期 |
1994.06.21 |
申请号 |
US19910708866 |
申请日期 |
1991.05.31 |
申请人 |
MERCIAN CORPORATION |
发明人 |
ARISAWA, AKIRA;KAWAMURA, NAOTO;KOJIMA, IKUO;OKAMURA, KAZUHIKO;TONE, HIROSHI;OKAMOTO, ROKURO |
分类号 |
C07H17/08;C12N1/21;C12N9/10;C12N15/55;C12N15/76;C12P19/62;(IPC1-7):C12P21/06;A01N37/18;C07H19/00 |
主分类号 |
C07H17/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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