Oral compositions possessing antiplaque and antigingivitis properties containing stannous fluoride stabilized with stannous gluconate are described herein. The composition contains: (a) a safe and effective amount of stannous fluoride; (b) a safe and effective amount of stannous gluconate; and (c) a pharmaceutically acceptable carrier wherein the pH of said composition is from about 3.0 to about 5.0 and said composition is substantially free of a calcium ion source(s).
申请公布号
CA1330047(C)
申请公布日期
1994.06.07
申请号
CA19880577349
申请日期
1988.09.14
申请人
PROCTER & GAMBLE COMPANY (THE)
发明人
MAJETI, SATYANARAYANA;GUAY, CHRISTOPHER B.;CRISANTI, MARK M.