| 发明名称 |
Inhibitors of farnesyl-protein transferase |
| 摘要 |
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras. |
| 申请公布号 |
AU5455394(A) |
申请公布日期 |
1994.05.24 |
| 申请号 |
AU19940054553 |
申请日期 |
1993.10.28 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
S. JANE DESOLMS;SAMUEL L. GRAHAM;JOHN SUIMAN WAI |
| 分类号 |
A61K31/195;A61K31/215;A61K31/365;A61P35/00;A61P35/02;A61P43/00;C07C323/25;C07C323/39;C07C323/49;C07C323/59;C07C323/67;C07D307/33 |
主分类号 |
A61K31/195 |
| 代理机构 |
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