A prostaglandin E1 analogue represented by formula wherein R1 represents a hydrogen atom or a C1-C6 alkyl group; and X is an oxygen atom and R2 represents or , or X is a sulfur atom and R2 represents . The compound has a strong and prolonged inhibitory action for platelet aggregation and is useful for treatment of various thrombotic diseases including peripheral circulatory disturbance.
申请公布号
CA2147461(A1)
申请公布日期
1994.04.28
申请号
CA19932147461
申请日期
1993.10.20
申请人
TAISHO PHARMACEUTICAL CO., LTD.;SATO, FUMIE
发明人
SATO, FUMIE;AMANO, TAKEHIRO;KAMEO, KAZUYA;TANAMI, TOHRU;MUTOH, MASARU;ONO, NAOYA;GOTO, JUN