| 摘要 |
<p>In accordance with the present invention, there is provided a new class of compounds which function as selective non-competitive inhibitors of neuronal nicotinic acetylcholine receptors, and compositions containing same. Invention compounds are highly specific for neuronal nicotinic acetylcholine receptors, blocking such receptors only after their activation by agonists. Also provided are methods to inhibit the action of neuronal nicotinic acetylcholine receptors and methods for reducing the neurological effects of nicotine in a subject addicted thereto.</p> |
