| 摘要 |
<p>A compound represented by general formula (I) or a pharmaceutically acceptable salt thereof, and a pancytopenia remedy containing the same as the active ingredient, wherein X represents =N- or =C-; R1 to R3 represent each hydrogen, halogen, alkyl or alkoxy; Z represents -O-, -S- or -NR- (R being hydrogen or alkyl); R?4 and R5¿ represent each hydrogen, alkyl, aminoalkyl, mono- or dialkylaminoalkyl, hydroxyalkyl or acyloxyalkyl, or alternatively R?4 and R5¿ are combined together to represent a cyclic group; R6 represents (a), (b), (c), (d), (e) or (f); A?1, A2, A6 and A7¿ represent each a single bond or alkylene; A?3, A4 and A8¿ represent each alkylene; A5 represents a single bond or -O-; R?7, R8, R17, R20 and R21¿ represent each optionally substituted alkyl, cycloalkyl, cycloalkylalkyl, aryl or phenylalkyl, provided that R?7 and R8¿ may further represent each hydrogen, alkenyl or acyl, and R?20 and R21¿ may further represent each hydrogen; and R?15, R16, R18 and R19¿ represent each hydrogen, halogen, OH, NO¿2?, NH2, alkyl, alkoxy, cycloalkyl or cycloalkylalkyl, provided that R?15 and R16¿ may be combined together to represent a cyclic group.</p> |
