| 摘要 |
The present invention relates to a process for chromatographically concentrating and separating a component of a multi-component feedstream using a magnetically stabilized fluidized bed. More particularly, the present invention concerns an isomobility focusing process wherein a feedstream is introduced into a magnetically stabilized bed of magnetizable solids for which the component to be separated has an affinity, the solids descending countercurrently to the ascending flow of a fluidizing medium, the feedstream and the fluidizing medium together comprising a fluid phase within the column, under conditions wherein the component is concentrated within at least one isomobility focusing zone within the column, wherein such zone an equilibrium is maintained between the velocity of the component in the fluid phase and the velocity of the component on the solid phase. Conditions of temperature, pH or salt concentration are adjusted such that the desired component is purified and concentrated as it is introduced into the column. The desired component is removed from the column as a sidestream or by elution with an eluent. |
