发明名称 |
Screening method for controlling agranulocytosis |
摘要 |
A screening method for detecting the vulnerability of patients on clozapine therapy to developing agranulocytosis which comprises establishing the concentration of N-desmethylclozapine in the blood or bone marrow of said patient. In addition, a method of determining patient sensitivity to N-desmethylclozapine is provided which comprises collecting heparinized blood and assaying it for stem cell sensitivity to N-desmethylclozapine.
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申请公布号 |
US5300422(A) |
申请公布日期 |
1994.04.05 |
申请号 |
US19910802162 |
申请日期 |
1991.12.04 |
申请人 |
CASE WESTERN RESERVE UNIVERSITY |
发明人 |
GERSON, STANTON L.;MELTZER, HERBERT |
分类号 |
G01N33/94;(IPC1-7):C12Q1/00;G01N33/48 |
主分类号 |
G01N33/94 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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