发明名称 |
Carbohydrate-based anti-inflammatory agents. |
摘要 |
<p>Ligands that bind to human selectin receptors are disclosed. The ligands are formulated with excipient carriers to form compositions which are administered to treated condition such as inflammation. The ligands have the structural formula III <CHEM> or molecules which have hydrogen bond donor groups equivalent to the circled groups with respect to their ability to form hydrogen bonds with a selectin under physiological conditions.</p> |
申请公布号 |
EP0589556(A2) |
申请公布日期 |
1994.03.30 |
申请号 |
EP19930306071 |
申请日期 |
1993.07.30 |
申请人 |
GLYCOMED, INCORPORATED |
发明人 |
BRANDLEY, BRIAN K.;TIEMEYER, MICHAEL;SWIEDLER, STUART J.;MORELAND, MARGARET;SCHWEINGRUBER, HANS;NARASINGA, RAO |
分类号 |
A61K31/70;A61K31/7008;A61K31/7012;A61K31/702;A61K31/7028;A61K47/36;A61K47/48;A61K49/00;A61K51/08;A61M5/32;A61P29/00;C07H3/06;C07H5/04;C07H7/027;C07H13/04;C07H15/04;C07H15/10;C07K14/00;C07K14/705;C08B37/00;G01N33/53;G01N33/566;G01N33/569;G01N33/68;(IPC1-7):C07H13/04 |
主分类号 |
A61K31/70 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|