4-hydroxy-2-cyclopentenone derivative and carcinostatic and osteogenesis promoter containing the same

摘要

An optically active compound represented by general formula (I), a mixture thereof, and a carcinostatic and osteogenesis promoter each containing the same as the active ingredient, wherein Y represents hydrogen or halogen; A represents hydroxy, C2-C7 acyloxy, C2-C5 alkoxycarbonyloxy or C1-C7 sulfonyloxy and B represents hydrogen, or alternatively A and B are combined together to represent a bond; R<2> represents a C4-C10 alicyclic hydrocarbon, C6-C10 aromatic hydrocarbon or C1-C9 heterocyclic hydrocarbon group each of which may be substituted; R<3> represents hydrogen or a C1-C10 aliphatic hydrocarbon, C4-C10 alicyclic hydrocarbon or C6-C10 aromatic hydrocarbon group each of which may be substituted; R<4> represents hydrogen, C1-C4 alkyl, C2-C7 acyl, C2-C5 alkoxycarbonyl, tri(C1-C7 hydrocarbyl)silyl or a group which forms an acetal bond together with the oxygen atom to which the R<4> is bonded; and R<5> represents hydrogen or a C1-C10 aliphatic hydrocarbon or C4-C10 alicyclic hydrocarbon group each of which may be substituted.