发明名称 |
STABILIZATION OF t-PA pro. |
摘要 |
Pharmaceutical compositions containing non-glycosylated human tissue type plasminogen activator (t-PA) having enzymatic activity of at least 0.1 MU/ml are disclosed. The compositions have a pH of from 4.5 to 6, contain citrate, and at least one other compound. |
申请公布号 |
EP0458939(B1) |
申请公布日期 |
1994.03.23 |
申请号 |
EP19910901285 |
申请日期 |
1990.12.19 |
申请人 |
BOEHRINGER MANNHEIM GMBH |
发明人 |
KOHNERT, ULRICH, DR.;RUDOLPH, RAINER, DR. |
分类号 |
A61K38/46;A61K38/49;A61K47/12;A61K47/16;A61K47/18;A61K47/20;A61K47/22;A61K47/26;A61K47/42;A61P7/02 |
主分类号 |
A61K38/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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