DNA SEQUENCES INVOLVED IN THE SECONDARY METABOLITE BIOSYNTHESIS BY MYXOBACTERIA

摘要

The present invention primarily relates to a DNA fragment which can be obtained from the gene cluster, which is responsible for soraphen biosynthesis, within the genome of (S. cellulosum) and comprises at least one gene or a part of a gene which codes for a polypeptide which is involved directly or indirectly in the biosynthesis of soraphen, and to methods for the preparation of said DNA fragment. The present invention further more relates to recombinant DNA molecules which comprise one of the DNA fragments according to the invention, and to the plasmids and vectors derived therefrom. Likewise embraced are host organisms which are transformed with said plasmid DNA or vector DNA.