发明名称 Peptides derived from trifluoromethyl ketones, process for their preparation and the pharmaceutical compositions which contain them
摘要 New cycloalkylalkylamines, which are ligands for sigma receptors, of formula (I) <IMAGE> in which, R1 is H or lower alkyl; X and Y are H, OH, lower alkyl, lower alkoxy, halogen or nitrile; V1 and V2 together form a double bond bonded to an oxygen or to a hydroxyimino radical or are bonded in an ethylenedioxy chain; A is a valency bond, an oxygen, or a methylene or ethylene group; m is 0, 1 or 2, and n varies from 1 to 5. Psychotropic medicament which is also useful in gastroenterology.
申请公布号 ZA9305434(B) 申请公布日期 1994.02.22
申请号 ZA19930005434 申请日期 1993.07.29
申请人 ADIR ET COMPAGNIE 发明人 MICHEL VINCENT;GUILLAUME DE NANTEUIL;GEORGES REMOND;BERNARD PORTEVIN;YOLANDE HERVE;EMMANUEL CANET;MICHEL LONCHAMPT
分类号 A61K31/13;A61K31/15;A61K31/275;A61K31/35;A61K31/352;A61K31/357;A61P1/04;A61P25/00;A61P25/02;A61P25/18;C07C211/38;C07C215/42;C07C225/18;C07C251/44;C07D311/22;C07D311/32;C07D311/68;C07D317/72;C07D493/10 主分类号 A61K31/13
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