发明名称 THERAPY OF NERVE DEGENERATIVE DISEASE
摘要 PURPOSE: To obtain a treating drug for a neurodegeneration disease, especially Alzheimer type senile dementia or Parkinsonism contg. a compd. such asα- nornicotine as an effective component. CONSTITUTION: This treating drug for a neurodegeneration disease, especially a disease causing cholinergic incompetence contains a compd. represented by the formula (where R' is an alkyl, X is a halo or an alkyl, 0<=m<=4 and 0<=n<=6), preferablyα-nornicotine as an effective component. The effective amt. of the compd. is at least 5 to <150μg per 1 kg body weight of a patient and the compd. is preferably administered to a patient by at least 0.10 to <10 mg/hr.
申请公布号 JPH0632736(A) 申请公布日期 1994.02.08
申请号 JP19930135086 申请日期 1993.05.14
申请人 R J REYNOLDS TOBACCO CO 发明人 PATORITSUKU MAIKERU RIPIERO;UIRIAMU SUKOTSUTO KOORUDOUERU
分类号 A61K31/44;A61K31/4427;A61K31/465;A61P25/00;A61P25/28;C07D401/04;(IPC1-7):A61K31/44 主分类号 A61K31/44
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