发明名称 Methods of using (-) cisapride for the treatment of gastro-esophageal reflux disease and other disorders
摘要 A composition comprising (-) cisapride, or a pharmaceutically acceptable salt thereof, wherein the composition is for eliciting an antiemetic effect in a human by administering an amount thereof sufficient to alleviate nausea and vomiting whilst being insufficient to cause adverse side-effects associated with the administration of racemic cisapride, or while achieving a higher bioavailability than achieved with racemic cisapride; or the composition is for treating a condition caused by gastrointestinal motility dysfunction in a human by administering an amount thereof sufficient to alleviate said condition whilst being insufficient to cause adverse side-effects associated with the administration of racemic cisapride, or while achieving a higher bioavailability than achieved with racemic cisapride, and wherein the (-)-cisapride or pharmaceutically acceptable salt thereof comprises at least 90% by weight of the total amount of cisapride in the composition.
申请公布号 AU4666393(A) 申请公布日期 1994.01.31
申请号 AU19930046663 申请日期 1993.07.06
申请人 SEPRACOR INC. 发明人 NANCY M GRAY;JAMES W YOUNG
分类号 C07D211/62;A61K31/445;A61K31/4468;A61P1/00;A61P1/08;A61P1/10;A61P1/14 主分类号 C07D211/62
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