| 摘要 |
PCT No. PCT/NL93/00140 Sec. 371 Date Feb. 28, 1995 Sec. 102(e) Date Feb. 28, 1995 PCT Filed Jul. 2, 1993 PCT Pub. No. WO94/01092 PCT Pub. Date Jan. 20, 1994Composition for delayed release of an active substance, such as a medicament, the active substance being incorporated in a polysaccharide matrix which is formed by an essentially crystalline straight-chain glucan, in particular an alpha -glucan which has a helix structure, such as amylodextrin or a fraction having a helix structure obtained from amylose V. The composition can contain an amount of active substance of from 0.1 to 80% by weight and the active substance can, depending of the hydrophilicity, have a molecular weight of up to 500 to 1500 daltons. The active substance is released from the composition at a constant rate. |
