Novel crystal of monohydrate of heterocyclic bis(phosphonic acid) derivative,申请号AU19930043566-传众专利搜索

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发明名称	Novel crystal of monohydrate of heterocyclic bis(phosphonic acid) derivative
摘要	Crystal D or E of 1-hydroxy-2-(imidazo[1,2-a]-pyridin-3-yl)ethane-1,1-bis(phosphonic acid) monohydrate having specified lattice spacing and relative intensity in the powder X-ray diffraction spectrum obtained by using Cu-K alpha radiation and a dehydration peak temperature of 135-149 DEG C or 160-170 DEG C according to TG-DSC thermogravimetric analysis; and a solid pharmaceutical preparation containing the same. The crystals are useful for producing a stable solid preparation of the above compound which has an excellent drug efficacy for diseases wherein increased bone resorption participates, such as osteoporosis.
申请公布号	AU4356693(A)	申请公布日期	1994.01.24
申请号	AU19930043566	申请日期	1993.06.18
申请人	YAMANOUCHI PHARMACEUTICAL CO., LTD.	发明人	YASUO ISOMURA;MAKOTO TAKEUCHI;MAMORU HAMADA;YOSHISABURO KANEKO;NORIYA YAMAMOTO
分类号	A61K31/675;C07F9/6561	主分类号	A61K31/675
代理机构		代理人
主权项
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