发明名称 COMPOSITION FOR CONTROLLED RELEASE OF AN ACTIVE SUBSTANCE AND METHOD FOR THE PREPARATION OF SUCH A COMPOSITION
摘要 Composition for delayed release of an active substance, such as a medicament, the active substance being incorporated in a polysaccharide matrix which is formed by an essentially crystalline straight-chain glucan, in particular an .alpha.-glucan which has a helix structure, such as amylodextrin or a fraction having a helix structure obtained from amylose V. The composition can contain an amount of active substance of from 0.1 to 80 % by weight and the active substance can, depending on the hydrophilicity, have a molecular weight of up to 500 or 1500 daltons. The active substance is released from the composition at a constant rate.
申请公布号 CA2139494(A1) 申请公布日期 1994.01.20
申请号 CA19932139494 申请日期 1993.07.02
申请人 TNO 发明人 BESEMER ARIE C;LERK COENRAAD F
分类号 A61K9/22;A61K9/20;A61K9/26;A61K47/36;(IPC1-7):A61K47/36 主分类号 A61K9/22
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