Immobilisiertes Enzympräparat und seine Verwendung.
摘要
A stabilised enzyme preparation comprising an immobilised hydantoinase is useful for the preparation of a D(-)(optionally substituted phenyl)glycine or N-carbamoyl derivative thereof by hydrolysis of a 5-(optionally substituted phenyl)hydantoin. The enzyme preparation comprises cells or treated cells of a hydantoinase - producing organism immobilised within or on a suitable solid support, or an enzyme derived from the organism adsorbed on or bonded to a polymeric support, together with divalent metal ions which stabilise the preparation and render it capable of re-use. Processes for preparing the enzyme preparation and for using it to prepare commercially impor tant end products such as D(-)(4-hydroxyphenyl)glycine are described.
申请公布号
DE3786511(T2)
申请公布日期
1994.01.13
申请号
DE19873786511T
申请日期
1987.09.09
申请人
BEECHAM GROUP P.L.C., BRENTFORD, MIDDLESEX, GB
发明人
POWELL, LAWSON WILLIAM, WORTHING WEST SUSSEX, BN14 8QH, GB;POWER, JOHN ANTHONY, FAVERSHAM KENT ME13 7JW, GB