Processes for detecting the presence of neoplastic disease are provided. The processes involve the detection of a product associated with expression of genes that encode protein receptors for fibroblast growth factor in cells or a product indicative of elevated levels of a fibroblast growth factor receptor in a body fluid. Detection can be carried out in a variety of ways, including hybridization to detect the presence of mRNA encoding a growth factor receptor or immunological assays to detect the presence of receptor protein. Kits for performing the processes are also provided.
申请公布号
WO9400599(A2)
申请公布日期
1994.01.06
申请号
WO1993US05703
申请日期
1993.06.14
申请人
WHITTIER INSTITUTE FOR DIABETES AND ENDOCRINOLOGY;PRIZM PHARMACEUTICALS, INC.
发明人
NOVA, MICHAEL, PHILIP;GONZALEZ, ANA-MARIA;BAIRD, J., ANDREW